Allergic reaction to eye drop preservatives?

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Allergic reaction to eye drop preservatives?

Postby E.H. » Fri Mar 23, 2007 8:57 am

Hi,

I am the person they write statistics about. Ya know...that 1 in a million person who experiences the unexpected. I had PRK lasik 6 weeks ago. My 1st. day checkup went exceptionally well. I could read the bottom line on the chart. However on the 3rd. day after using 3 different eyedrops 4X a day, I could barely open my eyes and could not see anything but shapes. I had to call the operator to ask them to connect me to the Docs office. It was very scary.

Turns out I was having a severe allergic reaction to the preservatives in all 3 eyedrops. My vision is still very blurry and today I was told I have some corneal haze in my right eye. I asked the Doc if the eyedrops could have damaged the formation of new cells. He replied, "He didn't think so but it definately caused severe inflammation which affected my healing process". He wants me to wait until my 3 month checkup before he determines final vision results.

Obviously I am very nervous. Is there anyone on this website that has experienced an allergic reaction such as mine? Did it affect your long term PRK Lasik results? Is there a medical professional willing to give me their opinion if a severe allergic reaction could have permanently affected my vision? Scarred my eyes? Caused the corneal haze? Etc.? Thanks
Last edited by E.H. on Fri Mar 23, 2007 8:50 pm, edited 3 times in total.
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Re: Allergic reaction to eye drop preservatives?

Postby LasikExpert » Fri Mar 23, 2007 4:11 pm

E.H. wrote:Is there anyone on this website that has experienced an allergic reaction such as mine?


Severe allergic reactions are document in medical literature, but like you said, they are very, very rare.

E.H. wrote:Did it affect your long term PRK Lasik results?


It is possible, depending upon how the body reacted to the insult of the allergen. You really won't know until after 3-6 months. Edema (swelling) of the cornea is very likely in a situation like this. Edema will temporarily change your refractive error. As the edema resolves with healing, the temporary change in refractive error will also resolve.

E.H. wrote:Is there a medical professional willing to give me their opinion if a severe allergic reaction could have permanently affected my vision?


I recommend that you ask your PRK doctor for a referral to a corneal specialist for an evaluation. I highly suspect the corneal specialist will also state that you will need to wait 3-6 months to know what will happen, but you would have the peace of mind that multiple doctors have the same opinion.

E.H. wrote:Scarred my eyes? Caused the corneal haze? Etc.?


It seems most likely that the cornea’s response was to accelerate the movement and development of cells to fight the insult of the allergen. These cells can cause the cornea to become hazy. With the insult removed, these cells would naturally dissipate. It is probable that after 3-6 months the cornea will clear, but it is also possible that the cornea will remain hazy to some degree. Hopefully it would be haze that does not disrupt your vision quality.

I personally experienced a similar reaction with my PRK, although it was not exactly an allergic reaction. After about two months the quality of my vision started to return, although the haze was still visible upon examination by the doctor. At six months all haze had dissipated.
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