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Autoimmune Disorder and Immunocompromised

Considerations with Lasik, All-Laser Lasik, PRK, LASEK, Epi-Lasik, CK, P-IOL, RLE, etc.


lasik
Autoimmune disorders are a contraindication for Lasik due to the disorder and possible interaction with meds.

 

Autoimmune disorders (ie: rheumatoid arthritis, lupus Scleroderma, Sjogren's syndrome erythematosus, thyroiditis, pernicious anemia, Addison's disease, insulin-dependent type-1 diabetes mellitus, dermatomyositis, Crohn's disease, sclerosis, Raynaud’s, Multiple sclerosis, HIV, AIDS) are specifically cited as contraindications for conventional or custom wavefront Lasik, All-Laser Lasik, PRK, LASEK, and Epi-Lasik. Autoimmune disorders may not be as problematic for RLE, P-IOLs or other refractive surgery procedures, however many the individual circumstances of the patient would need to be evaluated.

Autoimmune disorders are diseases caused by the body producing an immune response against its own tissues. The cause of autoimmune diseases is unknown, but it appears that there is an inherited predisposition to develop autoimmune disease in many cases. The concern with Lasik and similar refractive surgery is that the body may respond to the surgical manipulation of the cornea in unexpected ways. Unexpected and unwanted responses are not consistent from disorder to disorder, nor are they consistent from patient to patient with the same disorder.

Although the FDA lists autoimmune disorders as a contraindication for laser eye surgery, doctors may perform the procedure if in their medical opinion the surgery is appropriate. This is an off-label use of the medical device, which is legal when medically appropriate. There are many individuals with autoimmune disorders who have had successful Lasik and other refractive surgery. If you have an autoimmune disorder you need to discuss this in detail with any prospective refractive surgeon, plus with your primary care physician and neurologist.

If you are ready to choose a doctor to be evaluated for conventional or custom wavefront Lasik, All-Laser Lasik, PRK, LASEK, Epi-Lasik, NearVision CK, RLE, or any refractive surgery procedure, we highly recommend you consider a doctor who has been evaluated and certified by the USAEyes nonprofit organization. Locate a USAEyes Evaluated & Certified Lasik Laser Eye Surgeon.


Current Autoimmune Medical Journal News...

Laser-assisted intrastromal keratomileusis in a patient with systemic mastocytosis.

Related Articles

Laser-assisted intrastromal keratomileusis in a patient with systemic mastocytosis.

Optometry. 2008 Feb;79(2):95-7

Authors: Myrowitz EH

BACKGROUND: The U.S. Food and Drug Administration (FDA), and more recently the American Academy of Ophthalmology (AAO), list relative and absolute contraindications to laser-assisted intrastromal keratomileusis (LASIK). The AAO guidelines consider connective tissue or autoimmune diseases and systemic immunosuppresion as relative contraindications and only uncontrolled diseases and uncontrolled ocular allergy as absolute contraindications. Recent reports concluded that LASIK could be performed effectively and safely in selected patients with stable and controlled systemic diseases. Reported here is a case of successful LASIK with 3 years follow-up in the setting of systemic mastocytosis. CASE REPORT: A 42-year-old woman with moderate myopia and astigmatism underwent bilateral LASIK. Her medical history was significant for systemic mastocytosis. Five days after surgery, a diffuse lamellar keratopathy (DLK) 1+ was observed in the left eye and treated successfully with prednisolone acetate. The patient achieved visual acuity of 20/20 in each eye unaided. These findings were stable at 7, 12, 18, and 36 months after surgery. She continues to use olopatadine. CONCLUSION: Because of the rare nature of systemic mastocytosis and the anaphalactoid mechanism of release of mast cells, it may be difficult to assess the risk of undergoing LASIK. Any known or suspected triggers must be avoided. The use of an antihistamine and mast cell stabilizer, as used in this case, may have a beneficial effect.

PMID: 18215799 [PubMed - indexed for MEDLINE]


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Last updated Thursday, February 25, 2010

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