The Pezman wrote:If I understand that correctly, this means that LASEK attempts to maintain most of the corneal thickness, whereas PRK just destroys it outright. If that's the case, wouldn't LASEK ultimately be the surgery which leaves your eyes the closest to how they were?
The epitheliaum is the soft thin outermost layer of the cornea. Epithelial cells do not contribute to the structural integrity of the cornea. The amount of structual cornea removed by a laser is exactly the same in LASEK and PRK.
In both LASEK and PRK the epithelial cells are mortally wounded. All of them die off and are replaced by new cells. Corneal epithelial cells are the fastest reproducing cells in the human body. In PRK the cells are removed during the surgery and are replaced by new cells. In LASEK the dead and dying cells are repositioned back over the cornea, slough off, and are replaced by new cells. The amount of epithelal cells that die and are replaced are exactly the same in PRK and LASEK.
The only difference between PRK and LASEK is that the dead and dying epithelial cells are repositioned over the cornea in LASEK, and removed in PRK. THe reason LASEK has a bit of a roller coaster ride vision recovery is the process of sloughing off the dead cells and replacing them with new ones. PRK just needs to grow new cells. PRK does not need to get anything out of its way to create a new epithelium.
LASEK was developed to resolve a limitation of PRK, which is corneal haze for higher corrections and patient discomfort. It was thought that putting the dead cells back over the cornea would act like a "bandage" and reduce the probability of haze and patient discomfort. There have been several studies that show vision recover at three and six months is exactly the same with LASEK and PRK. Additionally, many studies affirm that there is virtually no difference in patient discomfort between PRK and LASEK.
In my opinion, and the opinion of many fine surgeons, LASEK is just so much expensive luggage.