Anyman wrote:Alphagan gives me relief, but I have read one dare not use it for longer periods due to a rebound effect or loss of efficacy.
The first peer-reviewed paper on pupil size reduction for night vision issues with Alphagan was written by
Jay McDonald, MD (a surgeon certified by our organization) in early 2003. The use of Alphagan for pupil size issues was initiated in the general ophthalmic population during the several months prior to publication of this first study in the
Journal of Cataract and Refractive Surgery. Follow-up studies have been performed by other doctors from Tel Aviv, Germany, Brasil, and Korea, being published in 2004, 2005, 2007, and 2008 . None of these studies report a rebound effect or loss of efficacy. It appears the information you have read is anecdotal and is not supported with scientific evidence, but I'd be interested in any peer-reviewed study that has this finding.
Alphagan P is commonly prescribed as a glaucoma control medication. The most common dosage is one drop in the eye three times a day. Alphagan P for pupil size issues is commonly used only as needed and would conceivably be once each day in the evening as its pupil constricting effects tend to last for about six hours. Alphagan P can be used by glaucoma patients in significantly larger doses than used for halo effects for the life of the patient. I find no adverse effects that realate exclusively to long-term use (medication interatction, allergey, etc. notwithstanding).
Anyman wrote:He said that nobody has them after 4-6 months. Guess what? He is either grossly mistaken or he lied.
At best, the statement is incomplete. People who do not use effective treatment for halos will continue to have them; treatment including corrective lenses (glasses or contacts), enhancement surgery to resolve residual refractive error, Alphagan P for scotopic pupil size reduction, or pilocarpine for aggressive pupil size reduction.
Anyman wrote:Can't use alphagan for the next 50 years & contacts give only some relief.
Actually, it appears that you can use Alphagan for the next 50 years. That may not be desired and it certainly was not the goal of your Lasik, but it appears to be a viable response to the halo problem you experience.
Anyman wrote:I still say that pupil size serve as a predictor. When my pupils are smaller I have no issues. It stands to reason that if one's operated zone is smaller than the pupil then one can see the transition.
Your reasoning may be intuitive, but multiple studies at multiple locations throughout the world have shown that it is wrong. Pupil size is a moderator of halos for patients who have the effect, but pupil size is not a reliable predictor of who will or who will not have halos.
Anyman wrote:How often does one hear of smaller pupil people having this disability?
Not often, but the occurrence has been well documented.
Anyman wrote:I say stay far, far away from this procedure if one has even slightly larger pupils. Not worth the risk.
I have warned many people that they may have an elevated risk of night vision disturbances like halos due to large pupils, high refractive correction, high astigmatism, small ablation zone, flat corneas, etc., but whether or not it is an acceptable risk is going to be the decision of the patient. The best we can do is make the patient aware of the potential problem. Discussing your situation in this forum goes to that end.