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Lasik Doctors

 

Epi-Lasik Laser Eye Surgery

Comparison to Lasik, All-Laser Lasik, LASEK, and PRK


Click to see video of Epi-Lasik. Similar to PRK and LASEK, Epi-Lasik creates a flap of the epithelium that is moved aside and replaced over the area treated with the excimer laser. Click for video.

 

Epi-Lasik is a relatively new version of surface ablation like PRK that is more similar to LASEK with some distinct advantages over Lasik and All-Laser Lasik. A microkeratome with a blunt blade is utilized to mechanically cleave the epithelium from the Bowman’s membrane, leaving an expose area for excimer laser ablation. Epi-Lasik preserves the structural integrity of the stroma and is heralded as minimizing patient discomfort when compared to PRK and LASEK, shorten the length of time before visual recovery, and reduce the incidence of corneal haze associated with other surface ablation procedures, such as PRK and LASEK.

Laser refractive surgery has gone through an evolution beginning in the early 1990s with PRK. PRK uses an excimer laser was fired directly through the Bowman's layer and into the stromal layer of the cornea to reshape its curvature effecting the refraction of the patient. PRK tended to be very uncomfortable because of the eye's wound response. Discomfort continues until the epithelium grew back over the ablated area. Newer techniques limit patient discomfort, but rarely eliminate discomfort completely. Additionally, because of corneal haze due to wound response, the safe refractive change with PRK was limited to approximately + 3 D to -6 D correction. Newer techniques have expanded that range, but corneal haze is still an issue that needs to be accommodated.

Lasik was the next evolution in laser refractive surgery. Lasik involves a precise incision into the stromal layer of the cornea, creating a flap. The flap is lifted exposing the stroma, where the excimer laser ablates the tissue, reshaping the curvature from within. Lasik effectively fools the cornea into not knowing that it has surgery, so the procedure is virtually painless and given the control of the depth of flap, Lasik has the ability to correct a much wider range of correction (+5D to -15D). While Lasik solved many of the issues surrounding PRK and widened the range of correction, it has its own set of complications and refractive issues. The majority of the complications relate to the flap itself and the optical aberrations, which are attributed to it.

Ever in search of a better procedure, ophthalmology returned to surface ablation solutions, primarily LASEK. The primary methodology around this procedure was to attempt to separate the epithelial layer from the top of the cornea, ablate the underlying tissue with the excimer laser and replace the epithelium on top of the cornea making it act as a biological bandage contact lens. This greatly reduced the pain seen in PRK and eliminated the flap-related issues plaguing Lasik. Although LASEK reportedly improved patient comfort and reduced the probability of corneal haze, the alcohol solution required to release the epithelial cells from the underlying cornea mortally wounds all cells, delaying vision recovery and creating an unstable epithelial layer until the cells are replaced.

Epi-Lasik attempts to provide the best of both Lasik and PRK/LASEK. By using a blunt blade to lift the epithelium in a single sheet, the epithelium is a much more viable entity. The repositioned epithelium acts as a bandage while the underlying cornea heals. Although current studies are inconclusive if patient outcomes are better with Epi-Lasik when compared to PRK or LASEK, many studies have shown that the surface ablation class of Epi-Lasik, LASEK, and PRK provides better outcomes than Lasik and All-Laser Lasik.

If you are ready to choose a doctor to be evaluated for conventional or custom wavefront Lasik, All-Laser Lasik, PRK, LASEK, Epi-Lasik, NearVision CK, RLE, or any refractive surgery procedure, we highly recommend you consider a doctor who has been evaluated and certified by the USAEyes nonprofit organization. Locate a USAEyes Evaluated & Certified Lasik Laser Eye Surgery Doctor.

If this article did not fully answer your questions, use our free Ask Lasik Expert patient forum.

Video courtesy University of Illinois Eye & Ear Infirmary.


Current Epi-Lasik Medical Journal News...

Comparison of real-time intraocular pressure during laser in situ keratomileusis and epithelial laser in situ keratomileusis in porcine eyes.

Related Articles

Comparison of real-time intraocular pressure during laser in situ keratomileusis and epithelial laser in situ keratomileusis in porcine eyes.

J Cataract Refract Surg. 2010 Mar;36(3):477-482

Authors: Hernández-Verdejo JL, de Benito-Llopis L, Teus MA

PURPOSE: To compare real-time intraocular pressure (IOP) between laser in situ keratomileusis (LASIK) and epithelial LASIK (epi-LASIK) in porcine eyes during flap creation using a microkeratome or an epikeratome, respectively. SETTING: Vissum Madrid, Madrid, Spain. METHODS: In this prospective study, a Moria microkeratome was used in 1 eye (LASIK group) and an Epi-K epikeratome in the other eye (epi-LASIK group) to create a lamellar corneal flap and an epithelial flap, respectively, in freshly enucleated porcine eyes. The IOP changes during the procedures were recorded by direct cannulation using a reusable blood pressure transducer connected to the anterior chamber. RESULTS: Each group comprised 17 eyes. In the LASIK group, the mean IOP was 113.65 mm Hg +/- 10.78 (SD) during suctioning and 112.35 +/- 11.51 mm Hg during cutting phases. The mean duration of the phases was 9.00 +/- 1.46 seconds and 6.06 +/- 1.14 seconds, respectively. In the epi-LASIK group, the mean IOP was 92.57 +/- 20.86 mm Hg during suctioning, 82.09 +/- 20 mm Hg during cutting, and 67.28 +/- 13.49 during low vacuum. The mean duration of the phases was 25.88 +/- 1.96 seconds, 33.82 +/- 2.81 seconds, and 29.71 +/- 3.29 seconds, respectively. The IOP values were significantly different between the 2 groups (all comparisons P<.05). CONCLUSION: Real-time IOP measured during suctioning and flap creation by direct cannulation of the anterior chamber in freshly enucleated porcine eyes showed a significant increase in IOP during LASIK and epi-LASIK; the increase was lower in the epi-LASIK group. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.

PMID: 20202548 [PubMed - as supplied by publisher]

 


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Last updated Thursday, February 25, 2010

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