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Epi-Lasik Laser Eye Surgery

Comparison to Lasik, All-Laser Lasik, LASEK, and PRK


Click to see video of Epi-Lasik. Similar to PRK and LASEK, Epi-Lasik creates a flap of the epithelium that is moved aside and replaced over the area treated with the excimer laser. Click for video.

 

Epi-Lasik is a relatively new version of surface ablation like PRK that is more similar to LASEK with some distinct advantages over Lasik and All-Laser Lasik. A microkeratome with a blunt blade is utilized to mechanically cleave the epithelium from the Bowman’s membrane, leaving an expose area for excimer laser ablation. Epi-Lasik preserves the structural integrity of the stroma and is heralded as minimizing patient discomfort when compared to PRK and LASEK, shorten the length of time before visual recovery, and reduce the incidence of corneal haze associated with other surface ablation procedures, such as PRK and LASEK.

Laser refractive surgery has gone through an evolution beginning in the early 1990s with PRK. PRK uses an excimer laser was fired directly through the Bowman's layer and into the stromal layer of the cornea to reshape its curvature effecting the refraction of the patient. PRK tended to be very uncomfortable because of the eye's wound response. Discomfort continues until the epithelium grew back over the ablated area. Newer techniques limit patient discomfort, but rarely eliminate discomfort completely. Additionally, because of corneal haze due to wound response, the safe refractive change with PRK was limited to approximately + 3 D to -6 D correction. Newer techniques have expanded that range, but corneal haze is still an issue that needs to be accommodated.

Lasik was the next evolution in laser refractive surgery. Lasik involves a precise incision into the stromal layer of the cornea, creating a flap. The flap is lifted exposing the stroma, where the excimer laser ablates the tissue, reshaping the curvature from within. Lasik effectively fools the cornea into not knowing that it has surgery, so the procedure is virtually painless and given the control of the depth of flap, Lasik has the ability to correct a much wider range of correction (+5D to -15D). While Lasik solved many of the issues surrounding PRK and widened the range of correction, it has its own set of complications and refractive issues. The majority of the complications relate to the flap itself and the optical aberrations, which are attributed to it.

Ever in search of a better procedure, ophthalmology returned to surface ablation solutions, primarily LASEK. The primary methodology around this procedure was to attempt to separate the epithelial layer from the top of the cornea, ablate the underlying tissue with the excimer laser and replace the epithelium on top of the cornea making it act as a biological bandage contact lens. This greatly reduced the pain seen in PRK and eliminated the flap-related issues plaguing Lasik. Although LASEK reportedly improved patient comfort and reduced the probability of corneal haze, the alcohol solution required to release the epithelial cells from the underlying cornea mortally wounds all cells, delaying vision recovery and creating an unstable epithelial layer until the cells are replaced.

Epi-Lasik attempts to provide the best of both Lasik and PRK/LASEK. By using a blunt blade to lift the epithelium in a single sheet, the epithelium is a much more viable entity. The repositioned epithelium acts as a bandage while the underlying cornea heals. Although current studies are inconclusive if patient outcomes are better with Epi-Lasik when compared to PRK or LASEK, many studies have shown that the surface ablation class of Epi-Lasik, LASEK, and PRK provides better outcomes than Lasik and All-Laser Lasik.

If you are ready to choose a doctor to be evaluated for conventional or custom wavefront Lasik, All-Laser Lasik, PRK, LASEK, Epi-Lasik, NearVision CK, RLE, or any refractive surgery procedure, we highly recommend you consider a doctor who has been evaluated and certified by the USAEyes nonprofit organization. Locate a USAEyes Evaluated & Certified Lasik Laser Eye Surgery Doctor.

If this article did not fully answer your questions, use our free Ask Lasik Expert patient forum.

Video courtesy University of Illinois Eye & Ear Infirmary.


Current Epi-Lasik Medical Journal News...

Early postoperative pain and visual outcomes following epipolis-laser in situ keratomileusis and photorefractive keratectomy.

Related Articles

Early postoperative pain and visual outcomes following epipolis-laser in situ keratomileusis and photorefractive keratectomy.

Korean J Ophthalmol. 2010 Jun;24(3):143-7

Authors: Kim JH, Lee J, Kim JY, Tchah H

PURPOSE: To compare early postoperative pain and visual outcomes after epipolis-laser in situ keratomileusis (epi-LASIK) and photorefractive keratectomy (PRK) in the treatment of myopia. METHODS: A retrospective chart review was designed and included 49 eyes in 30 patients who underwent epi-LASIK and 54 eyes in 29 patients who underwent PRK. During the early postoperative period (days 1 to 5), pain, uncorrected visual acuity (UCVA), and time to epithelial healing were recorded. Visual outcomes were followed for up to six months. RESULTS: Mean preoperative spherical equivalent refraction for the epi-LASIK group was -3.99+/-1.39 diopters (D) and that of the PRK group was -3.54+/-1.27 D. The pain scores on the fourth postoperative day were significantly higher in the epi-LASIK group than in the PRK group (p=0.017). Duration of pain in the epi-LASIK group was longer than in the PRK group (p=0.010). Mean healing time was significantly longer in the epi-LASIK group than in the PRK group (p<0.000). In addition, UCVA in the epi-LASIK group at postoperative days 1 and 3 were significantly lower than those in the PRK group (p=0.021 and p<0.000, respectively). Uncorrected visual acuity at one week and one month after epi-LASIK were lower than those after PRK (p=0.023 and p=0.004, respectively). CONCLUSIONS: In the epi-LASIK patients, pain relief, corneal healing, and visual recovery seemed to be slower during the early postoperative period compared to those of the PRK patients. With longer duration of follow-up, however, there were no significant differences in visual outcome between the two groups.

PMID: 20532139 [PubMed - in process]

 


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Last updated Monday, April 12, 2010

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